Book , Print in English

Microbiology

David R. Wessner, Davidson College, Christine Dupont, University of Waterloo, Trevor Charles, University of Waterloo.
  • Hoboken, NJ : Wiley, [2013]
  • xxxi, 867, [57] pages : illustrations (some color) ; 29 cm
  • Eisenhower C Level
    QR41.2.W47 2013 QUARTO c. 1
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Subjects
Medical Subjects
Genre
  • Lehrbuch.
Contents
  • note: 1. Microbial World
  • 1.1. Microbes
  • Toolbox 1.1 Polymerase Chain Reaction Amplification Of rRNA Genes
  • Mini-Paper: A Focus On The Research The Three Domains Of Life
  • 1.2. Microbial Genetics
  • Perspective 1.1 Creating Life In The Laboratory: The Miller-Urey Experiment
  • Perspective 1.2 Ribozymes: Evidence For An RNA-Based World
  • 1.3. Microbial Metabolism And Ecology
  • 1.4. Microbes And Disease
  • 2. Bacteria
  • 2.1. Morphology Of Bacterial Cells
  • 2.2. Cytoplasm
  • 2.3. Bacterial Cytoskeleton
  • 2.4. Cell Envelope
  • Perspective 2.1 Marvelous Magnetosomes!
  • Toolbox 2.1 The Gram Stain
  • Perspective 2.2 The Protective Shells Of Endospores
  • Mini-Paper: A Focus On The Research: New Microscopy Methods Reveal A Periplasm In Gram-Positive Bacterial Cells
  • 2.5. Bacterial Cell Surface
  • 2.6. Bacterial Taxonomy
  • 3. Eukaryal Microbes
  • 3.1. Morphology Of Typical Eukaryal Cells
  • Mini-Paper: A Focus On The Research Lipid Rafts: Organized Clustering Of Lipids Within A Membrane
  • Toolbox 3.1 Using Microscopy To Examine Cell Structure
  • Perspective 3.1 Hijacking The Cytoskeleton
  • 3.2. Diversity Of Eukaryal Microbes
  • 3.3. Replication Of Eukaryal Microbes
  • 3.4. Origin Of Eukaryal Cells
  • Perspective 3.2 Exploiting A Shared Evolutionary History With Plants In The Treatment Of Malaria
  • 3.5. Interactions Between Eukaryal Microbes And Animals, Plants, And The Environment
  • 4. Archaea
  • 4.1. Distinct Properites Of Archaea
  • 4.2. Archaeal Cell Structure
  • Toolbox 4.1 Vaccine Delivery Strategies
  • 4.3. Diversity Of Archaea
  • Perspective 4.1 Extremophiles And Biotechnology
  • Mini-Paper: A Focus On The Research The Role Of Archaeons In Our Digestive System
  • 5. Viruses
  • 5.1. Basic Overview Of Viruses
  • 5.2. Origins Of Viruses
  • 5.3. Cultivation, Purification, And Quantification Of Viruses
  • Toolbox 5.1 Cell Culture Techniques
  • Perspective 5.1 Measurement Of HIV Viral Load
  • 5.4. Diversity Of Viruses
  • Toolbox 5.2 Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)
  • 5.5. Virus-Like Particles
  • 5.6. Virology Today
  • Mini-Paper: A Focus On The Research New Findings In The Packaging Of DNA By The Model Bacteriophage T4
  • 6. Cultivating Microorganisms
  • 6.1. Nutritional Requirements Of Microorganisms
  • 6.2. Factors Affecting Microbial Growth
  • Toolbox 6.1 Phenotype Microarrays For Examining Microbial Growth
  • 6.3. Growing Microorganisms In The Laboratory
  • Perspective 6.1 The Discovery Of Heliobacter Pylori
  • Toolbox 6.2 Fishing For Uncultivated Microbes
  • Mini-Paper: A Focus On The Research Bringing To Life The Previously Unculturable Using The Soil Substrate Membrane System (SSMS)
  • 6.4. Measuring Microbial Population Growth
  • Perspective 6.2 Mycobacterium Leprae, An Extraordinarily Slow-Growing Pathogen
  • Perspective 6.3 The Human Intestine-A Continuous Culture
  • 6.5. Eliminating Microbes And Preventing Their Growth
  • 7. DNA Replication And Gene Expression
  • 7.1. Role Of DNA
  • 7.2. DNA Replication
  • 7.3. Transcription
  • Toolbox 7.1 Using A Gel Shift Assay To Identify DNA-Binding Proteins
  • 7.4. Translation
  • 7.5. Effects Of Mutations
  • Mini-Paper: A Focus On The Research Telomeres With Promoter Activity
  • Perspective 7.1 Using Mutations To Control Viral Infections
  • 8. Viral Replication Strategies
  • 8.1. Recognition Of Host Cells
  • Toolbox 8.1 The Western Blot
  • 8.2. Viral Entry And Uncoating
  • 8.3. Viral Replication
  • 8.4. Viral Assembly And Egress
  • 8.5. Antiviral Drugs
  • Perspective 8.1 DNA Microarrays And The SARS Virus
  • Mini-Paper: A Focus On The Research The Discovery Of Reverse Transcriptase
  • 9. Bacterial Genetic Analysis
  • 9.1. Bacteria As Subjects Of Genetic Research
  • 9.2. Mutations, Mutants, And Strains
  • Toolbox 9.1 Isolating Nutritional Mutants
  • 9.3. Restriction Enzymes, Vectors, And Cloning
  • 9.4. Recombination And DNA Transfer
  • Perspective 9.1 Plasmids That Produce Pathogens
  • Mini-Paper: A Focus On Type Research The Discovery Of Transduction
  • 10. Microbial Genomics
  • 10.1. Genome Sequencing
  • Perspective 10.1 Rate Of DNA Sequencing
  • Toolbox 10.3 Genome Databases
  • 10.2. Genomic Analysis Of Gene Expression
  • 10.3. Comparative Genomics
  • Perspective 10.2 The Minimal Genome
  • Mini-Paper: A Focus On The Research Genome Sequence Of A Killer Bug
  • 10.4. Metagenomics
  • 11. Regulation Of Gene Expression
  • 11.1. Differential Gene Expression
  • 11.2. Operon
  • 11.3. Global Gene Regulation
  • Mini-Paper: A Focus On The Research Tuning Promoters For Use In Synthetic Biology
  • Perspective 11.1 The Use Of Lactose Analogs In Gene Expression Studies
  • 11.4. Post-Initiation Of Gene Expression
  • Toolbox 11.1 Using RNA Molecules To Decrease Gene Expression
  • 11.5. Quorum Sensing
  • 11.6. Two-Component Regulatory Systems
  • 11.7. Chemotaxis
  • 12. Microbial Biotechnology
  • 12.1. Microbes For Biotechnology
  • Perspective 12.1 Bioprospecting: Who Owns The Microbes?
  • 12.2. Molecular Genetic Modification
  • Toolbox 12.1 Site-Directed Mutagenesis
  • Toolbox 12.2 Fusion Protein Purification
  • Mini-Paper: A Focus On The Research Making A Synthetic Genome
  • Perspective 12.2 The International Genetically Engineered Machine (IGEM) Competition, Standard Biological Parts, And Synthetic Biology
  • 12.3. Red Biotechnology
  • 12.4. White Biotechnology
  • Perspective 12.3 Biofuels: Biodiesel And Algae
  • 12.5. Green Biotechnology
  • Toolbox 12.3 Plant Transformation Using Bacteria
  • 13. Metabolism
  • 13.1. Energy, Enzymes, And ATP
  • Perspective 13.1 Who Needs Vitamins?
  • 13.2. Central Processes In ATP Synthesis
  • 13.3. Carbon Utilization In Microorganisms
  • 13.4. Respiration And The Electron Transport System
  • Perspective 13.2 Electricigenic Bacteria And Microbial Fuel Cells
  • 13.5. Metabolism Of Non-Glucose Carbon Sources
  • Toolbox 13.1 Metabolism And Rapid Bacterial Identification Systems
  • 13.6. Phototrophy And Photosynthesis
  • 13.7. Nitrogen And Sulfur Metabolism
  • 13.8. Biosynthesis Of Cellular Components
  • Mini-Paper: A Focus On The Research Genome Sequence Of A Deep Sea Symbiont
  • 14. Biogeochemical Cycles
  • 14.1. Nutrient Cycling
  • Toolbox 14.1 Using Microarrays To Examine Microbial Communities: The Geochip
  • 14.2. Cycling Driven By Carbon Metabolism
  • Perspective 14.1 CO2 As A Greenhouse Gas And Its Influence On Climate Change
  • 14.3. Cycling Driven By Nitrogen Metabolism
  • Mini-Paper: A Focus On The Research The First Isolation And Cultivation Of A Marine Archaeon
  • 14.4. Interconnectedness Of Cycles
  • Perspective 14.2 The Microbiology Of Environmentally Toxic Acid Mine Drainage
  • 15. Microbial Ecosystems
  • 15.1. Microbes In The Environment
  • 15.2. Microbial Community Structure
  • Toolbox 15.1 Flow Cytometry
  • Mini-Paper: A Focus On The Research A Method For The Identification Of Catabolic Genes From Metagenomic Libraries Based On Their Gene Expression Characteristics
  • Perspective 15.1 Naming The Unculturable And Uncharacterized
  • 15.3. Aquatic Ecosystems
  • Perspective 15.2 Dead Zones
  • 15.4. Terrestrial Ecosystems
  • 15.5. Deep Subsurface And Geothermal Ecosystems
  • 16. Microbiology Of Food And Water
  • 16.1. Food Spoilage
  • 16.2. Food Preservation
  • 16.3. Food Fermentation
  • 16.4. Foodborne And Waterborne Illness
  • 16.5. Microbiological Aspects Of Water Quality
  • Perspective 16.1 Implication Of Sludge Bulking
  • Toolbox 16.1 Measuring Biochemical Oxygen Demand (BOD)
  • Mini-Paper: A Focus On The Research Enhanced Biological Removal Of Phosphorus
  • 17. Microbial Symbionts
  • 17.1. Types Of Microbe-Host Interactions
  • 17.2. Symbionts Of Plants
  • 17.3. Lichens
  • 17.4. Symbionts Of Vertebrates
  • Toolbox 171 Germfree And Gnotobiotic Animals
  • Perspective 17.1 Probiotics-Do They Work?
  • Mini-Paper: A Focus On The Research Do Microbes Cause Obesity?
  • Perspective 17.2 Cows Contribute To Climate Change
  • 17.5. Symbionts Of Invertebrates
  • Perspective 17.3 Midichlorians-Not Just For Jedi
  • Perspective 17.4 Death Of Coral Reefs
  • 18. Introduction To Infectious Diseases
  • 18.1. Pathogenic Microbes
  • Toolbox 18.1 Measuring The Virulence Of Pathogens
  • 18.2. Virulence Strategies
  • Perspective 18.1 Host Defenses In Bacteria
  • 18.3. Transmission Of Infectious Diseases
  • 18.4. Proving Cause And Effect In Microbial Infections
  • Perspective 18.2 The Armadillo An Ideal Animal Model?
  • 18.5. Evolution Of Pathogens
  • Mini-Paper: A Focus On The Research Epidemiogy Of An Infectious Disease
  • 19. Innate Host Defenses Against Microbial Invasion
  • 19.1. Immunity
  • 19.2. Barriers To Infection
  • Perspective 19.1 Messy Mucus
  • 19.3. Inflammatory Response
  • 19.4. Molecules Of Innate Immunity
  • Toolbox 19.1 The Complement Fixation Test
  • 19.5. Cells Of Innate Immunity
  • Perspective 19.2 Natural Born Killers
  • 19.6. Invertebrate Defenses
  • Mini-Paper: A Focus On The Research Mammalian Cells Can Recognize Bacterial DNA
  • Toolbox 19.2 The Limulus Amoebocyte Assay For LPS
  • 20. Adaptive Immunity
  • 20.1. Features Of Adaptive Immunity
  • 20.2. T Cells
  • 20.3. Antigen Processing
  • 20.4. Antigen-Presenting Cells
  • 20.5. Humoral And Cell-Mediated Immune Responses
  • Perspective 20.1 Too Much Of A Good Thing
  • Mini-Paper: A Focus On The Research Attempting To Engineer A Virus To Improve Immunocontraception
  • 20.6. B Cells And The Production Of Antibody
  • Perspective 20.2 Vaccines Against T-Independent Antigens --
  • Contents note continued: Toolbox 20.1 Monoclonal Antibody (mAb) Production
  • Toolbox 20.2 Enzyme-Linked Immunosorbent Assay (ELISA)
  • Perspective 20.3 Turning Antibody Upside Down
  • 21. Bacterial Pathogenesis
  • 21.1. Bacterial Virulence Factors
  • Mini-Paper: A Focus On The Research E. Coli Injects Its Own Receptor
  • Toolbox 21.1 Serotyping
  • Perspective 21.1 The Good, The Bad, And The Ugly Side Of Botulinum Toxin
  • Perspective 21.2 Superabsorbent Tampons And Superantigens
  • Perspective 21.3 Iron, Vampires, Fashion, And The White Plague
  • 21.2. Survival In The Host: Strategies And Consequences
  • Toolbox 21.2 The Tuberculin Test For Tuberculosis
  • 21.3. Evolution Of Bacterial Pathogens
  • Perspective 21.4 Antibiotics Trigger Toxins?
  • 22. Viral Pathogenesis
  • 22.1. Recurring Themes In Viral Pathogenesis
  • Perspective 22.1 Vertical Transmission Of HIV
  • 22.2. Interactions With The Host: Strategies And Consequences
  • Perspective 22.2 Viral Induction Of Apoptosis
  • 22.3. Viral Infections And Cancer
  • Toolbox 22.1 Immunoprecipitation
  • Perspective 22.3 SV40 And Human Cancers
  • Mini-Paper: A Focus On The Research Viruses That Cause Cancer By Affecting Cellular Proliferation
  • 22.4. Evolution Of Viral Pathogens
  • Perspective 22.4 Ethical Concerns About Avian Flu Research
  • 23. Eukaryal Microbe Pathogenesis
  • 23.1. Mechanisms Of Eukaryal Microbe Pathogenesis
  • Mini-Paper: A Focus On The Research An Experimental System For The Genomic Study Of Dutch Elm Disease
  • Perspective 23.1 Pneumocystis Jirovecii Or Carinii: The Evolving Field Of Taxonomy
  • Perspective 23.2 Magic Mushrooms
  • 23.2. Pathogen Study: Plasmodium Falciparum
  • Toolbox 23.1 Testing For Malaria
  • 23.3. Macroscopic Eukaryal Pathogens
  • 23.4. Evolution Of Eukaryal Pathogens
  • Perspective 23.3 Chytrid Fungus: An Emerging Fungal Pathogen
  • 24. Control Of Infectious Diseases
  • 24.1. Historical Aspects Of Infectious Disease Treatment And Control
  • 24.2. Antimicrobial Drugs
  • 24.3. Antimicrobial Drug Resistance
  • Toolbox 24.1 Drug Susceptibility Testing And MIC
  • Mini-Paper: A Focus On The Research Soil Microbes Possess Extensive Resistance To Antibiotics
  • Perspective 24.1 The Pursuit Of New Antibiotics: Why Bother?
  • Perspective 24.2 Health Care-Associated Infections: A Recipe For Resistance
  • Perspective 24.3 Phage Therapy: Biocontrol For Infections
  • 24.4. Predicting And Controlling Epidemics
  • Perspective 24.4 Variolation: Deliberate Infection With Smallpox Virus
  • 24.5. Immunization And Vaccines.
Other information
  • Includes bibliographical references and index.
Additional form
ISBN
  • 0471694347
  • 9780471694342
  • Alternate version: 9781118473825
Identifying numbers
  • LCCN: 2012038562
  • OCLC: 812070668
  • OCLC: 812070668